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Construction of a Triple-Gene Deletion Mutant of Orf Virus and Evaluation of Its Safety, Immunogenicity and Protective Efficacy
Contagious ecthyma is a zoonotic disease caused by the orf virus (ORFV). Since there is no specific therapeutic drug available, vaccine immunization is the main tool to prevent and control the disease. Previously, we have reported the construction of a double-gene deletion mutant of ORFV (rGS14ΔCBPΔ...
Autores principales: | Shen, Zhanning, Liu, Bo, Zhu, Zhen, Du, Jige, Zhou, Zhiyu, Pan, Chenfan, Chen, Yong, Yin, Chunsheng, Luo, Yufeng, Li, Huanrong, Chen, Xiaoyun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10224447/ https://www.ncbi.nlm.nih.gov/pubmed/37243014 http://dx.doi.org/10.3390/vaccines11050909 |
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