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Combination Therapy with UV-4B and Molnupiravir Enhances SARS-CoV-2 Suppression

The host targeting antiviral, UV-4B, and the RNA polymerase inhibitor, molnupiravir, are two orally available, broad-spectrum antivirals that have demonstrated potent activity against SARS-CoV-2 as monotherapy. In this work, we evaluated the effectiveness of UV-4B and EIDD-1931 (molnupiravir’s main...

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Detalles Bibliográficos
Autores principales: Franco, Evelyn J., Drusano, George L., Hanrahan, Kaley C., Warfield, Kelly L., Brown, Ashley N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10224493/
https://www.ncbi.nlm.nih.gov/pubmed/37243261
http://dx.doi.org/10.3390/v15051175