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Aggregation of Amyloidogenic Peptide Uperin—Molecular Dynamics Simulations

Uperin 3.5 is a remarkable natural peptide obtained from the skin of toadlets comprised of 17 amino acids which exhibits both antimicrobial and amyloidogenic properties. Molecular dynamics simulations were performed to study the β-aggregation process of uperin 3.5 as well as two of its mutants, in w...

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Detalles Bibliográficos
Autores principales: Ermakova, Elena, Makshakova, Olga, Kurbanov, Rauf, Ibraev, Ilya, Zuev, Yuriy, Sedov, Igor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10224498/
https://www.ncbi.nlm.nih.gov/pubmed/37241811
http://dx.doi.org/10.3390/molecules28104070