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A VLP-Based Vaccine Displaying HBHA and MTP Antigens of Mycobacterium tuberculosis Induces Protective Immune Responses in M. tuberculosis H37Ra Infected Mice

Heparin-binding hemagglutinin (HBHA) and M. tuberculosis pili (MTP) are important antigens on the surface of Mycobacterium tuberculosis. To display these antigens effectively, the fusion protein HBHA-MTP with a molecular weight of 20 kD (L20) was inserted into the receptor-binding hemagglutinin (HA)...

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Detalles Bibliográficos
Autores principales: Wang, Juan, Xie, Tao, Ullah, Inayat, Mi, Youjun, Li, Xiaoping, Gong, Yang, He, Pu, Liu, Yuqi, Li, Fei, Li, Jixi, Lu, Zengjun, Zhu, Bingdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10224509/
https://www.ncbi.nlm.nih.gov/pubmed/37243045
http://dx.doi.org/10.3390/vaccines11050941