The Structural Combination of SIL and MODAG Scaffolds Fails to Enhance Binding to α-Synuclein but Reveals Promising Affinity to Amyloid β

A technique to image α-synuclein (αSYN) fibrils in vivo is an unmet scientific and clinical need that would represent a transformative tool in the understanding, diagnosis, and treatment of various neurodegenerative diseases. Several classes of compounds have shown promising results as potential PET...

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Detalles Bibliográficos
Autores principales: Di Nanni, Adriana, Saw, Ran Sing, Bowden, Gregory D., Bidesi, Natasha S. R., Bjerregaard-Andersen, Kaare, Korat, Špela, Herth, Matthias M., Pichler, Bernd J., Herfert, Kristina, Maurer, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10224536/
https://www.ncbi.nlm.nih.gov/pubmed/37241742
http://dx.doi.org/10.3390/molecules28104001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10224536/
https://www.ncbi.nlm.nih.gov/pubmed/37241742
http://dx.doi.org/10.3390/molecules28104001

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