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Analysis of the Dissolution Mechanism of Drugs into Polymers: The Case of the PVP/Sulindac System

This paper is dealing with the dissolution mechanism of crystalline sulindac into amorphous Polyvinylpyrrolidone (PVP) upon heating and annealing at high temperatures. Special attention is paid on the diffusion mechanism of drug molecules in the polymer which leads to a homogeneous amorphous solid d...

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Detalles Bibliográficos
Autores principales: Latreche, Mansour, Willart, Jean-François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10224566/
https://www.ncbi.nlm.nih.gov/pubmed/37242747
http://dx.doi.org/10.3390/pharmaceutics15051505