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Side population cells derived from hUCMSCs and hPMSCs could inhibit the malignant behaviors of Tn(+) colorectal cancer cells from modifying their O-glycosylation status

BACKGROUND: Cosmc (C1GalT1C1) mutation could cause aberrant O-glycosylation and result in expression of Tn antigen on the surface of tumor cells (Tn(+) cells), which is associated with the metastasis and prognosis of cancer progression. Mesenchymal stem cells (MSCs) could participate in immunoregula...

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Detalles Bibliográficos
Autores principales: Hu, Wen, Ding, Ruisong, Wang, Mengyang, Huang, Panpan, Wei, Xia, Hu, Xingyou, Hu, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10224610/
https://www.ncbi.nlm.nih.gov/pubmed/37237420
http://dx.doi.org/10.1186/s13287-023-03334-3