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Side population cells derived from hUCMSCs and hPMSCs could inhibit the malignant behaviors of Tn(+) colorectal cancer cells from modifying their O-glycosylation status
BACKGROUND: Cosmc (C1GalT1C1) mutation could cause aberrant O-glycosylation and result in expression of Tn antigen on the surface of tumor cells (Tn(+) cells), which is associated with the metastasis and prognosis of cancer progression. Mesenchymal stem cells (MSCs) could participate in immunoregula...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10224610/ https://www.ncbi.nlm.nih.gov/pubmed/37237420 http://dx.doi.org/10.1186/s13287-023-03334-3 |