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Human Cytomegalovirus IE2 Disrupts Neural Progenitor Development and Induces Microcephaly in Transgenic Mouse

ABSTRACT: Human cytomegalovirus (HCMV) is a significant contributor to congenital birth defects. Limited by the lack of animal models, the pathogenesis of neurological damage in vivo caused by HCMV infection and the role of individual viral genes remain to be elucidated. Immediate early (IE2) protei...

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Detalles Bibliográficos
Autores principales: Niu, Delei, Zhang, Xianjuan, Zhang, Shuyun, Fan, Tianyu, Zhou, Xiaoqiong, Wang, Hui, Zhang, Xueming, Nan, Fulong, Jiang, Shasha, Liu, Fengjun, Wang, Yunyang, Wang, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10224843/
https://www.ncbi.nlm.nih.gov/pubmed/36991278
http://dx.doi.org/10.1007/s12035-023-03310-1