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Inference of cell type-specific gene regulatory networks on cell lineages from single cell omic datasets

Cell type-specific gene expression patterns are outputs of transcriptional gene regulatory networks (GRNs) that connect transcription factors and signaling proteins to target genes. Single-cell technologies such as single cell RNA-sequencing (scRNA-seq) and single cell Assay for Transposase-Accessib...

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Detalles Bibliográficos
Autores principales: Zhang, Shilu, Pyne, Saptarshi, Pietrzak, Stefan, Halberg, Spencer, McCalla, Sunnie Grace, Siahpirani, Alireza Fotuhi, Sridharan, Rupa, Roy, Sushmita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10224950/
https://www.ncbi.nlm.nih.gov/pubmed/37244909
http://dx.doi.org/10.1038/s41467-023-38637-9