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Myeloid MyD88 restricts CD8(+) T cell response to radiation therapy in pancreatic cancer

Radiation therapy induces immunogenic cell death in cancer cells, whereby released endogenous adjuvants are sensed by immune cells to direct adaptive immune responses. TLRs expressed on several immune subtypes recognize innate adjuvants to direct downstream inflammatory responses in part via the ada...

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Detalles Bibliográficos
Autores principales: Medler, Terry R., Blair, Tiffany C., Alice, Alejandro F., Dowdell, Alexa K., Piening, Brian D., Crittenden, Marka R., Gough, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10224952/
https://www.ncbi.nlm.nih.gov/pubmed/37244938
http://dx.doi.org/10.1038/s41598-023-35834-w