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Myeloid MyD88 restricts CD8(+) T cell response to radiation therapy in pancreatic cancer
Radiation therapy induces immunogenic cell death in cancer cells, whereby released endogenous adjuvants are sensed by immune cells to direct adaptive immune responses. TLRs expressed on several immune subtypes recognize innate adjuvants to direct downstream inflammatory responses in part via the ada...
Autores principales: | Medler, Terry R., Blair, Tiffany C., Alice, Alejandro F., Dowdell, Alexa K., Piening, Brian D., Crittenden, Marka R., Gough, Michael J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10224952/ https://www.ncbi.nlm.nih.gov/pubmed/37244938 http://dx.doi.org/10.1038/s41598-023-35834-w |
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