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RNA-Seq–based transcriptome analysis of corneal endothelial cells derived from patients with Fuchs endothelial corneal dystrophy

Fuchs endothelial corneal dystrophy (FECD) is the most common inherited corneal disease. Fibrillar focal excrescences called guttae and corneal edema due to corneal endothelial cell death result in progressive vision loss. Multiple genetic variants have been reported, but the pathogenesis of FECD is...

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Detalles Bibliográficos
Autores principales: Nakagawa, Tatsuya, Tokuda, Yuichi, Nakano, Masakazu, Komori, Yuya, Hanada, Naoya, Tourtas, Theofilos, Schlötzer-Schrehardt, Ursula, Kruse, Friedrich, Tashiro, Kei, Koizumi, Noriko, Okumura, Naoki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10224979/
https://www.ncbi.nlm.nih.gov/pubmed/37244951
http://dx.doi.org/10.1038/s41598-023-35468-y