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RNA-Seq–based transcriptome analysis of corneal endothelial cells derived from patients with Fuchs endothelial corneal dystrophy
Fuchs endothelial corneal dystrophy (FECD) is the most common inherited corneal disease. Fibrillar focal excrescences called guttae and corneal edema due to corneal endothelial cell death result in progressive vision loss. Multiple genetic variants have been reported, but the pathogenesis of FECD is...
Autores principales: | Nakagawa, Tatsuya, Tokuda, Yuichi, Nakano, Masakazu, Komori, Yuya, Hanada, Naoya, Tourtas, Theofilos, Schlötzer-Schrehardt, Ursula, Kruse, Friedrich, Tashiro, Kei, Koizumi, Noriko, Okumura, Naoki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10224979/ https://www.ncbi.nlm.nih.gov/pubmed/37244951 http://dx.doi.org/10.1038/s41598-023-35468-y |
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