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Directionality of developing skeletal muscles is set by mechanical forces

Formation of oriented myofibrils is a key event in musculoskeletal development. However, the mechanisms that drive myocyte orientation and fusion to control muscle directionality in adults remain enigmatic. Here, we demonstrate that the developing skeleton instructs the directional outgrowth of skel...

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Detalles Bibliográficos
Autores principales: Sunadome, Kazunori, Erickson, Alek G., Kah, Delf, Fabry, Ben, Adori, Csaba, Kameneva, Polina, Faure, Louis, Kanatani, Shigeaki, Kaucka, Marketa, Dehnisch Ellström, Ivar, Tesarova, Marketa, Zikmund, Tomas, Kaiser, Jozef, Edwards, Steven, Maki, Koichiro, Adachi, Taiji, Yamamoto, Takuya, Fried, Kaj, Adameyko, Igor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10224984/
https://www.ncbi.nlm.nih.gov/pubmed/37244931
http://dx.doi.org/10.1038/s41467-023-38647-7