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Evolutionarily recent retrotransposons contribute to schizophrenia

Transposable elements (TEs) are mobile genetic elements that constitute half of the human genome. Recent studies suggest that polymorphic non-reference TEs (nrTEs) may contribute to cognitive diseases, such as schizophrenia, through a cis-regulatory effect. The aim of this work is to identify sets o...

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Detalles Bibliográficos
Autores principales: Modenini, Giorgia, Abondio, Paolo, Guffanti, Guia, Boattini, Alessio, Macciardi, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10224989/
https://www.ncbi.nlm.nih.gov/pubmed/37244930
http://dx.doi.org/10.1038/s41398-023-02472-9