Dual synergistic inhibition of COX and LOX by potential chemicals from Indian daily spices investigated through detailed computational studies

Cyclooxygenase (COX) and Lipoxygenase (LOX) are essential enzymes for arachidonic acid (AA) to eicosanoids conversion. These AA-derived eicosanoids are essential for initiating immunological responses, causing inflammation, and resolving inflammation. Dual COX/5-LOX inhibitors are believed to be pro...

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Detalles Bibliográficos
Autores principales: Rudrapal, Mithun, Eltayeb, Wafa Ali, Rakshit, Gourav, El-Arabey, Amr Ahmed, Khan, Johra, Aldosari, Sahar M., Alshehri, Bader, Abdalla, Mohnad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10224994/
https://www.ncbi.nlm.nih.gov/pubmed/37244921
http://dx.doi.org/10.1038/s41598-023-35161-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10224994/
https://www.ncbi.nlm.nih.gov/pubmed/37244921
http://dx.doi.org/10.1038/s41598-023-35161-0

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