The inhibitory receptors PD1, Tim3, and A2aR are highly expressed during mesoCAR T cell manufacturing in advanced human epithelial ovarian cancer

BACKGROUND: Chemotherapy and surgery have been the mainstays of epithelial ovarian cancer (EOC) treatment so far. Cellular immunotherapies such as CAR T cell therapy have recently given hope of a cure for solid tumors like EOC. However, extrinsic factors associated with the CAR T cell manufacturing...

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Detalles Bibliográficos
Autores principales: Akbari, Behnia, Soltantoyeh, Tahereh, Shahosseini, Zahra, Yarandi, Fariba, Hadjati, Jamshid, Mirzaei, Hamid Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10225096/
https://www.ncbi.nlm.nih.gov/pubmed/37244991
http://dx.doi.org/10.1186/s12935-023-02948-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10225096/
https://www.ncbi.nlm.nih.gov/pubmed/37244991
http://dx.doi.org/10.1186/s12935-023-02948-0

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