Cargando…

The inhibitory receptors PD1, Tim3, and A2aR are highly expressed during mesoCAR T cell manufacturing in advanced human epithelial ovarian cancer

BACKGROUND: Chemotherapy and surgery have been the mainstays of epithelial ovarian cancer (EOC) treatment so far. Cellular immunotherapies such as CAR T cell therapy have recently given hope of a cure for solid tumors like EOC. However, extrinsic factors associated with the CAR T cell manufacturing...

Descripción completa

Detalles Bibliográficos
Autores principales:	Akbari, Behnia, Soltantoyeh, Tahereh, Shahosseini, Zahra, Yarandi, Fariba, Hadjati, Jamshid, Mirzaei, Hamid Reza
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10225096/ https://www.ncbi.nlm.nih.gov/pubmed/37244991 http://dx.doi.org/10.1186/s12935-023-02948-0

Ejemplares similares

PGE2-EP2/EP4 signaling elicits mesoCAR T cell immunosuppression in pancreatic cancer
por: Akbari, Behnia, et al.
Publicado: (2023)

Genetic Modification of Cytokine Signaling to Enhance Efficacy of CAR T Cell Therapy in Solid Tumors
por: Ghahri-Saremi, Navid, et al.
Publicado: (2021)

Crosstalk between autophagy and metabolic regulation of (CAR) T cells: therapeutic implications
por: Panahi Meymandi, Ahmad Reza, et al.
Publicado: (2023)

Chimeric Antigen Receptor (CAR) T Cell Therapy for Metastatic Melanoma: Challenges and Road Ahead
por: Soltantoyeh, Tahereh, et al.
Publicado: (2021)

αPD-1-mesoCAR-T cells partially inhibit the growth of advanced/refractory ovarian cancer in a patient along with daily apatinib
por: Fang, Juemin, et al.
Publicado: (2021)

Prolonged Persistence of Chimeric Antigen Receptor (CAR) T Cell in Adoptive Cancer Immunotherapy: Challenges and Ways Forward
por: Jafarzadeh, Leila, et al.
Publicado: (2020)

Outsmarting trogocytosis to boost CAR NK/T cell therapy
por: Ramezani, Faezeh, et al.
Publicado: (2023)

Synthesis of Meso-Diarylaminocorroles via S(N)Ar Reactions
por: Ueta, Kento, et al.
Publicado: (2019)

Highly Efficient Generation of Transgenically Augmented CAR NK Cells Overexpressing CXCR4
por: Jamali, Arezoo, et al.
Publicado: (2020)

Genetic and pharmacological targeting of A2a receptor improves function of anti-mesothelin CAR T cells
por: Masoumi, Elham, et al.
Publicado: (2020)

Arrestins function in cAR1 GPCR-mediated signaling and cAR1 internalization in the development of Dictyostelium discoideum
por: Cao, Xiumei, et al.
Publicado: (2014)

Macro-, meso- and microstructural characterization of metallic lattice structures manufactured by additive manufacturing assisted investment casting
por: Carneiro, V. H., et al.
Publicado: (2021)

Effect of Bacterial Lipopolysaccharide Contamination on Gutta Percha- versus Resilon-Induced Human Monocyte Cell Line Toxicity
por: Hadjati, Jamshid, et al.
Publicado: (2015)

Adenosine Blockage in Tumor Microenvironment and Improvement of Cancer Immunotherapy
por: Arab, Samaneh, et al.
Publicado: (2019)

Global Manufacturing of CAR T Cell Therapy
por: Levine, Bruce L., et al.
Publicado: (2016)

Differential Effects of Inhibitory and Stimulatory Anti-HER2 Monoclonal Antibodies on AKT/ERK Signaling Pathways
por: Soltantoyeh, Tahereh, et al.
Publicado: (2018)

Mesos in action
por: Ignazio, Roger
Publicado: (2016)

Meso-neurectomy
Publicado: (1898)

Impact of Manufacturing Procedures on CAR T Cell Functionality
por: Watanabe, Norihiro, et al.
Publicado: (2022)

Mast cell activation is enhanced by Tim1:Tim4 interaction but not by Tim-1 antibodies
por: Phong, Binh, et al.
Publicado: (2016)

Oligoclonal T Cells Transiently Expand and Express Tim-3 and PD-1 Following Anti-CD19 CAR T Cell Therapy: A Case Report
por: Funk, Christopher Ronald, et al.
Publicado: (2018)

Magnetic Circular Dichroism of meso-Phenyl-Substituted Pd-Octaethylporphyrins
por: Gorski, A., et al.
Publicado: (2020)

Dual-inhibitory domain iCARs improve the efficiency of the AND-NOT gate CAR T strategy
por: Bangayan, Nathanael J., et al.
Publicado: (2023)

Efficacy and Safety of G2013 as a Novel Immunosuppressive Agent on Differentiation, Maturation and Function of Human Dendritic Cells
por: ARJOMAND FARD, Nazanin, et al.
Publicado: (2017)

Rapid manufacturing of non-activated potent CAR T cells
por: Ghassemi, Saba, et al.
Publicado: (2022)

Potential solutions for manufacture of CAR T cells in cancer immunotherapy
por: Blache, Ulrich, et al.
Publicado: (2022)

Tim Burton /
por: Marcos Arza, Marcos
Publicado: (2007)

Tim Lou
por: Lou, Hou Keong
Publicado: (2009)

Building applications on Mesos
por: Greenberg, David
Publicado: (2015)

The meso-genomic era
por: Semple, Colin AM, et al.
Publicado: (2001)

Tim1 and Tim3 are not essential for experimental allergic asthma
por: Barlow, J L, et al.
Publicado: (2011)

Competencies Development Strategy Using Augmented Reality for Self-Management of Learning in Manufacturing Laboratories (AR-ManufacturingLab)
por: Hernández-Rodríguez, Felipe, et al.
Publicado: (2023)

The cell density factor CMF regulates the chemoattractant receptor cAR1 in Dictyostelium
Publicado: (1996)

Apache Mesos essentials: build and execute robust and scalable applications using Apache Mesos
por: Kakadia, Dharmesh
Publicado: (2015)

An exchange coupled meso–meso linked vanadyl porphyrin dimer for quantum information processing
por: Ranieri, Davide, et al.
Publicado: (2022)

TIM-Finder: A new method for identifying TIM-barrel proteins
por: Si, Jing-Na, et al.
Publicado: (2009)

Mertk Interacts with Tim-4 to Enhance Tim-4-Mediated Efferocytosis
por: Moon, Byeongjin, et al.
Publicado: (2020)

Profiling the inhibitory receptors LAG-3, TIM-3, and TIGIT in renal cell carcinoma reveals malignancy
por: Takamatsu, Kimiharu, et al.
Publicado: (2021)

Study of the tumor microenvironment during breast cancer progression
por: Eftekhari, Rahil, et al.
Publicado: (2017)

Hot stamping advanced manufacturing technology of lightweight car body
por: Hu, Ping, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_vhtk24of95dvpvf2foveto2t8l