Genome-wide DNA methylation profiling of HPV-negative leukoplakia and gingivobuccal complex cancers

BACKGROUND: Gingivobuccal complex oral squamous cell carcinoma (GBC-OSCC) is an aggressive malignancy with high mortality often preceded by premalignant lesions, including leukoplakia. Previous studies have reported genomic drivers in OSCC, but much remains to be elucidated about DNA methylation pat...

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Detalles Bibliográficos
Autores principales: Inchanalkar, Mayuri, Srivatsa, Sumana, Ambatipudi, Srikant, Bhosale, Priyanka G., Patil, Asawari, Schäffer, Alejandro A., Beerenwinkel, Niko, Mahimkar, Manoj B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10225107/
https://www.ncbi.nlm.nih.gov/pubmed/37245006
http://dx.doi.org/10.1186/s13148-023-01510-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10225107/
https://www.ncbi.nlm.nih.gov/pubmed/37245006
http://dx.doi.org/10.1186/s13148-023-01510-z

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