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Genome-wide DNA methylation profiling of HPV-negative leukoplakia and gingivobuccal complex cancers
BACKGROUND: Gingivobuccal complex oral squamous cell carcinoma (GBC-OSCC) is an aggressive malignancy with high mortality often preceded by premalignant lesions, including leukoplakia. Previous studies have reported genomic drivers in OSCC, but much remains to be elucidated about DNA methylation pat...
Autores principales: | Inchanalkar, Mayuri, Srivatsa, Sumana, Ambatipudi, Srikant, Bhosale, Priyanka G., Patil, Asawari, Schäffer, Alejandro A., Beerenwinkel, Niko, Mahimkar, Manoj B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10225107/ https://www.ncbi.nlm.nih.gov/pubmed/37245006 http://dx.doi.org/10.1186/s13148-023-01510-z |
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