The neuroprotective N-terminal amyloid-β core hexapeptide reverses reactive gliosis and gliotoxicity in Alzheimer’s disease pathology models

BACKGROUND: Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by accumulation of extracellular amyloid beta (Aβ) and intracellular neurofibrillary tangles, leading to chronic activation of astrocytes and microglia and persistent neuroinflammation. Aβ-linked activatio...

Descripción completa

Detalles Bibliográficos
Autores principales: Lantz, Megan J., Roberts, Alyssa M., Delgado, Donovan D., Nichols, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10225108/
https://www.ncbi.nlm.nih.gov/pubmed/37245024
http://dx.doi.org/10.1186/s12974-023-02807-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10225108/
https://www.ncbi.nlm.nih.gov/pubmed/37245024
http://dx.doi.org/10.1186/s12974-023-02807-9

Ejemplares similares