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Anti-angiogenic drug aggravates the degree of anti-resorptive drug-based medication-related osteonecrosis of the jaw by impairing the proliferation and migration function of gingival fibroblasts

BACKGROUND: Long-term use of anti-resorptive or anti-angiogenic drugs in cancer patients with odontogenic infections may lead to medication-related osteonecrosis of the jaw (MRONJ). This study investigated whether anti-angiogenic agents aggravate MRONJ occurrence in anti-resorptive-treated patients....

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Detalles Bibliográficos
Autores principales: Zhao, Ning, Li, Qing-xiang, Wang, Yi-fei, Qiao, Qiao, Huang, Hong-yuan, Guo, Chuan-bin, Guo, Yu-xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10225109/
https://www.ncbi.nlm.nih.gov/pubmed/37245004
http://dx.doi.org/10.1186/s12903-023-03034-7