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Applying CRISPR-Cas9 screens to dissect hematological malignancies

Bit by bit, over the last few decades, functional genomic tools have been piecing together the molecular puzzle driving tumorigenesis in human patients. Nevertheless, our understanding of the role of several genes and regulatory elements that drive critical cancer-associated physiological processes...

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Detalles Bibliográficos
Autores principales: Iyer, Deepak Narayanan, Schimmer, Aaron D., Chang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10225491/
https://www.ncbi.nlm.nih.gov/pubmed/36355853
http://dx.doi.org/10.1182/bloodadvances.2022008966