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Applying CRISPR-Cas9 screens to dissect hematological malignancies
Bit by bit, over the last few decades, functional genomic tools have been piecing together the molecular puzzle driving tumorigenesis in human patients. Nevertheless, our understanding of the role of several genes and regulatory elements that drive critical cancer-associated physiological processes...
Autores principales: | Iyer, Deepak Narayanan, Schimmer, Aaron D., Chang, Hong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society of Hematology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10225491/ https://www.ncbi.nlm.nih.gov/pubmed/36355853 http://dx.doi.org/10.1182/bloodadvances.2022008966 |
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