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Arterial wall fibrosis in Takayasu arteritis and its potential for therapeutic modulation

Arterial wall damage in Takayasu arteritis (TAK) can progress despite immunosuppressive therapy. Vascular fibrosis is more prominent in TAK than in giant cell arteritis (GCA). The inflamed arterial wall in TAK is infiltrated by M1 macrophages [which secrete interleukin-6 (IL-6)], which transition to...

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Detalles Bibliográficos
Autores principales: Misra, Durga Prasanna, Singh, Kritika, Sharma, Aman, Agarwal, Vikas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10225504/
https://www.ncbi.nlm.nih.gov/pubmed/37256147
http://dx.doi.org/10.3389/fimmu.2023.1174249