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Mast cell marker gene signature: prognosis and immunotherapy response prediction in lung adenocarcinoma through integrated scRNA-seq and bulk RNA-seq

BACKGROUND: Mast cells, comprising a crucial component of the tumor immune milieu, modulate neoplastic progression by secreting an array of pro- and antitumorigenic factors. Numerous extant studies have produced conflicting conclusions regarding the impact of mast cells on the prognosis of patients...

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Detalles Bibliográficos
Autores principales: Zhang, Pengpeng, Liu, Jianlan, Pei, Shengbin, Wu, Dan, Xie, Jiaheng, Liu, Jinhui, Li, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10225553/
https://www.ncbi.nlm.nih.gov/pubmed/37256127
http://dx.doi.org/10.3389/fimmu.2023.1189520