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A metabolic shift toward glycolysis enables cancer cells to maintain survival upon concomitant glutamine deprivation and V-ATPase inhibition

It is widely known that most cancer cells display an increased reliance on glutaminolysis to sustain proliferation and survival. Combining glutamine deprivation with additional anti-cancer therapies is an intensively investigated approach to increase therapeutic effectiveness. In this study, we exam...

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Detalles Bibliográficos
Autores principales: Lengauer, Florian, Geisslinger, Franz, Gabriel, Antje, von Schwarzenberg, Karin, Vollmar, Angelika M., Bartel, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10225586/
https://www.ncbi.nlm.nih.gov/pubmed/37255933
http://dx.doi.org/10.3389/fnut.2023.1124678