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Physical activity impacts resting skeletal muscle myosin conformation and lowers its ATP consumption

It has recently been established that myosin, the molecular motor protein, is able to exist in two conformations in relaxed skeletal muscle. These conformations are known as the super-relaxed (SRX) and disordered-relaxed (DRX) states and are finely balanced to optimize ATP consumption and skeletal m...

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Detalles Bibliográficos
Autores principales: Lewis, Christopher T.A., Tabrizian, Lee, Nielsen, Joachim, Laitila, Jenni, Beck, Thomas N., Olsen, Mathilde S., Ognjanovic, Marija M., Aagaard, Per, Hokken, Rune, Laugesen, Simon, Ingersen, Arthur, Andersen, Jesper L., Soendenbroe, Casper, Helge, Jørn W., Dela, Flemming, Larsen, Steen, Sahl, Ronni E., Rømer, Tue, Hansen, Mikkel T., Frandsen, Jacob, Suetta, Charlotte, Ochala, Julien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10225618/
https://www.ncbi.nlm.nih.gov/pubmed/37227464
http://dx.doi.org/10.1085/jgp.202213268