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Calorie restriction and pravastatin administration during pregnancy in obese rhesus macaques modulates maternal and infant metabolism and infant brain and behavioral development

BACKGROUND: Maternal obesity has been associated with a higher risk of pregnancy-related complications in mothers and offspring; however, effective interventions have not yet been developed. We tested two interventions, calorie restriction and pravastatin administration, during pregnancy in a rhesus...

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Detalles Bibliográficos
Autores principales: Hasegawa, Yu, Kim, Danielle H. J., Zhang, Zhichao, Taha, Ameer Y., Capitanio, John P., Hogrefe, Casey E., Bauman, Melissa D., Golub, Mari S., Van de Water, Judy, VandeVoort, Catherine A., Walker, Cheryl K., Slupsky, Carolyn M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10225656/
https://www.ncbi.nlm.nih.gov/pubmed/37255938
http://dx.doi.org/10.3389/fnut.2023.1146804