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Integrated transcriptome and metabolome analysis to investigate the mechanism of intranasal insulin treatment in a rat model of vascular dementia

Introduction: Insulin has an effect on neurodegenerative diseases. However, the role and mechanism of insulin in vascular dementia (VD) and its underlying mechanism are unknown. In this study, we aimed to investigate the effects and mechanism of insulin on VD. Methods: Experimental rats were randoml...

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Detalles Bibliográficos
Autores principales: Tang, Liang, Wang, Yan, Gong, Xujing, Xiang, Ju, Zhang, Yan, Xiang, Qin, Li, Jianming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10225696/
https://www.ncbi.nlm.nih.gov/pubmed/37256231
http://dx.doi.org/10.3389/fphar.2023.1182803