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Reticular adhesions are assembled at flat clathrin lattices and opposed by active integrin α5β1

Reticular adhesions (RAs) consist of integrin αvβ5 and harbor flat clathrin lattices (FCLs), long-lasting structures with similar molecular composition as clathrin-mediated endocytosis (CME) carriers. Why FCLs and RAs colocalize is not known. Here, we show that RAs are assembled at FCLs in a process...

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Detalles Bibliográficos
Autores principales: Hakanpää, Laura, Abouelezz, Amr, Lenaerts, An-Sofie, Culfa, Seyda, Algie, Michael, Bärlund, Jenny, Katajisto, Pekka, McMahon, Harvey, Almeida-Souza, Leonardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10225744/
https://www.ncbi.nlm.nih.gov/pubmed/37233325
http://dx.doi.org/10.1083/jcb.202303107