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Glycerol as a precursor for hepatic de novo glutathione synthesis in human liver

BACKGROUND: Glycerol is a substrate for gluconeogenesis and fatty acid esterification in the liver, processes which are upregulated in obesity and may contribute to excess fat accumulation. Glycine and glutamate, in addition to cysteine, are components of glutathione, the major antioxidant in the li...

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Detalles Bibliográficos
Autores principales: Jin, Eunsook S., Malloy, Craig R., Sharma, Gaurav, Finn, Erin, Fuller, Kelly N.Z., Reyes, Yesenia Garcia, Lovell, Mark A., Derderian, Sarkis C., Schoen, Jonathan A., Inge, Thomas H., Cree, Melanie G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10225920/
https://www.ncbi.nlm.nih.gov/pubmed/37224695
http://dx.doi.org/10.1016/j.redox.2023.102749