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Glycerol as a precursor for hepatic de novo glutathione synthesis in human liver
BACKGROUND: Glycerol is a substrate for gluconeogenesis and fatty acid esterification in the liver, processes which are upregulated in obesity and may contribute to excess fat accumulation. Glycine and glutamate, in addition to cysteine, are components of glutathione, the major antioxidant in the li...
Autores principales: | Jin, Eunsook S., Malloy, Craig R., Sharma, Gaurav, Finn, Erin, Fuller, Kelly N.Z., Reyes, Yesenia Garcia, Lovell, Mark A., Derderian, Sarkis C., Schoen, Jonathan A., Inge, Thomas H., Cree, Melanie G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10225920/ https://www.ncbi.nlm.nih.gov/pubmed/37224695 http://dx.doi.org/10.1016/j.redox.2023.102749 |
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