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Impaired intracellular calcium homeostasis enhances protein O-GlcNAcylation and promotes vascular calcification and stiffness in diabetes

Vascular calcification is accelerated in patients with diabetes mellitus and increases risk of cardiovascular events and mortality. Vascular smooth muscle cells (VSMC) play a key role in regulating vascular tone and contribute significantly to the development of diabetic vasculopathy. In this study,...

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Detalles Bibliográficos
Autores principales: Zhang, Weiping, Sun, Yong, Yang, Youfeng, Chen, Yabing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10225928/
https://www.ncbi.nlm.nih.gov/pubmed/37230005
http://dx.doi.org/10.1016/j.redox.2023.102720