Combining skin and olfactory α-synuclein seed amplification assays (SAA)—towards biomarker-driven phenotyping in synucleinopathies

Seed amplification assays (SAA) are becoming commonly used in synucleinopathies to detect α-synuclein aggregates. Studies in Parkinson’s disease (PD) and isolated REM-sleep behavior disorder (iRBD) have shown a considerably lower sensitivity in the olfactory epithelium than in CSF or skin. To get an...

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Detalles Bibliográficos
Autores principales: Kuzkina, A., Rößle, J., Seger, A., Panzer, C., Kohl, A., Maltese, V., Musacchio, T., Blaschke, S. J., Tamgüney, G., Kaulitz, S., Rak, K., Scherzad, A., Zimmermann, P. H., Klussmann, J. P., Hackenberg, S., Volkmann, J., Sommer, C., Sommerauer, M., Doppler, K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10226020/
https://www.ncbi.nlm.nih.gov/pubmed/37248217
http://dx.doi.org/10.1038/s41531-023-00519-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10226020/
https://www.ncbi.nlm.nih.gov/pubmed/37248217
http://dx.doi.org/10.1038/s41531-023-00519-8

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