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Co-Administration of nalbuphine to improve morphine tolerance in mice with bone cancer pain

BACKGROUND: Kappa-opioid receptor (KOR) agonists are known for having opposite and/or different effects compared with Mu-opioid receptor (MOR) agonists. This study is aimed at clarifying the analgesic effect and tolerance of nalbuphine combined with morphine, and quantifying the mRNA and protein exp...

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Detalles Bibliográficos
Autores principales: Ren, Bingxu, Zhang, Jiannan, Yang, Xiaohu, Sun, Dapeng, Sheng, Duanyang, Fang, Qiang, Ji, Zhonghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10226037/
https://www.ncbi.nlm.nih.gov/pubmed/37226458
http://dx.doi.org/10.1177/17448069231178741