Small Molecules Targeting DNA Polymerase Theta (POLθ) as Promising Synthetic Lethal Agents for Precision Cancer Therapy

[Image: see text] Synthetic lethality (SL) is an innovative strategy in targeted anticancer therapy that exploits tumor genetic vulnerabilities. This topic has come to the forefront in recent years, as witnessed by the increased number of publications since 2007. The first proof of concept for the e...

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Detalles Bibliográficos
Autores principales: Pismataro, Maria Chiara, Astolfi, Andrea, Barreca, Maria Letizia, Pacetti, Martina, Schenone, Silvia, Bandiera, Tiziano, Carbone, Anna, Massari, Serena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10226047/
https://www.ncbi.nlm.nih.gov/pubmed/37134182
http://dx.doi.org/10.1021/acs.jmedchem.2c02101

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10226047/
https://www.ncbi.nlm.nih.gov/pubmed/37134182
http://dx.doi.org/10.1021/acs.jmedchem.2c02101

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