Non-steroidal CYP17A1 Inhibitors: Discovery and Assessment

[Image: see text] CYP17A1 is an enzyme that plays a major role in steroidogenesis and is critically involved in the biosynthesis of steroid hormones. Therefore, it remains an attractive target in several serious hormone-dependent cancer diseases, such as prostate cancer and breast cancer. The medici...

Descripción completa

Detalles Bibliográficos
Autores principales: Wróbel, Tomasz M., Jørgensen, Flemming Steen, Pandey, Amit V., Grudzińska, Angelika, Sharma, Katyayani, Yakubu, Jibira, Björkling, Fredrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10226049/
https://www.ncbi.nlm.nih.gov/pubmed/37191389
http://dx.doi.org/10.1021/acs.jmedchem.3c00442

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10226049/
https://www.ncbi.nlm.nih.gov/pubmed/37191389
http://dx.doi.org/10.1021/acs.jmedchem.3c00442

Ejemplares similares