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Antitumor efficacy of multi-target in situ vaccinations with CpG oligodeoxynucleotides, anti-OX40, anti-PD1 antibodies, and aptamers

To overcome immune tolerance to cancer, the immune system needs to be exposed to a multi-target action intervention. Here, we investigated the activating effect of CpG oligodeoxynucleotides (ODNs), mesyl phosphoramidate CpG ODNs, anti-OX40 antibodies, and OX40 RNA aptamers on major populations of im...

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Detalles Bibliográficos
Autores principales: Proskurina, Anastasia S., Ruzanova, Vera S., Ritter, Genrikh S., Efremov, Yaroslav R., Mustafin, Zakhar S., Lashin, Sergey A., Burakova, Ekaterina A., Fokina, Alesya A., Zatsepin, Timofei S., Stetsenko, Dmitry A., Leplina, Olga Y., Ostanin, Alexandr A., Chernykh, Elena R., Bogachev, Sergey S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial Department of Journal of Biomedical Research 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10226083/
https://www.ncbi.nlm.nih.gov/pubmed/37161885
http://dx.doi.org/10.7555/JBR.36.20220052