Cargando…
Antitumor efficacy of multi-target in situ vaccinations with CpG oligodeoxynucleotides, anti-OX40, anti-PD1 antibodies, and aptamers
To overcome immune tolerance to cancer, the immune system needs to be exposed to a multi-target action intervention. Here, we investigated the activating effect of CpG oligodeoxynucleotides (ODNs), mesyl phosphoramidate CpG ODNs, anti-OX40 antibodies, and OX40 RNA aptamers on major populations of im...
Autores principales: | Proskurina, Anastasia S., Ruzanova, Vera S., Ritter, Genrikh S., Efremov, Yaroslav R., Mustafin, Zakhar S., Lashin, Sergey A., Burakova, Ekaterina A., Fokina, Alesya A., Zatsepin, Timofei S., Stetsenko, Dmitry A., Leplina, Olga Y., Ostanin, Alexandr A., Chernykh, Elena R., Bogachev, Sergey S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Editorial Department of Journal of Biomedical Research
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10226083/ https://www.ncbi.nlm.nih.gov/pubmed/37161885 http://dx.doi.org/10.7555/JBR.36.20220052 |
Ejemplares similares
-
Phosphate-modif ied CpG oligonucleotides
induce in vitro maturation of human myeloid dendritic cells
por: Ostanin, A.A., et al.
Publicado: (2020) -
Theoretical premises of a “three in one” therapeutic approach to treat immunogenic and nonimmunogenic cancers: a narrative review
por: Proskurina, Anastasia S., et al.
Publicado: (2021) -
Chronometric Administration of Cyclophosphamide and a Double-Stranded DNA-Mix at Interstrand Crosslinks Repair Timing, Called “Karanahan” Therapy, Is Highly Efficient in a Weakly Immunogenic Lewis Carcinoma Model
por: Ruzanova, Vera, et al.
Publicado: (2022) -
Analysis of the Biological Properties of Blood Plasma Protein with GcMAF Functional Activity
por: Dolgova, Evgeniya V., et al.
Publicado: (2022) -
Defective Regulation of Membrane TNFα Expression in Dendritic Cells of Glioblastoma Patients Leads to the Impairment of Cytotoxic Activity against Autologous Tumor Cells
por: Tyrinova, Tamara, et al.
Publicado: (2020)