TRIM67 alleviates cerebral ischemia‒reperfusion injury by protecting neurons and inhibiting neuroinflammation via targeting IκBα for K63-linked polyubiquitination

BACKGROUND: Excessive and unresolved neuroinflammation plays an important role in the pathophysiology of many neurological disorders, such as ischemic stroke, yet there are no effective treatments. Tripartite motif-containing 67 (TRIM67) plays a crucial role in the control of inflammatory disease an...

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Detalles Bibliográficos
Autores principales: Yu, Yongbo, Xia, Qian, Zhan, Gaofeng, Gao, Shuai, Han, Tangrui, Mao, Meng, Li, Xing, Wang, Yonghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10226213/
https://www.ncbi.nlm.nih.gov/pubmed/37248543
http://dx.doi.org/10.1186/s13578-023-01056-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10226213/
https://www.ncbi.nlm.nih.gov/pubmed/37248543
http://dx.doi.org/10.1186/s13578-023-01056-w

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