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Development and validation of sensitive BCR::ABL1 fusion gene quantitation using next-generation sequencing
BACKGROUND: BCR::ABL1 fusion has significant prognostic value and is screened for chronic myeloid leukemia (CML) disease monitoring as a part of routine molecular testing. To overcome the limitations of the current standard real-time quantitative polymerase chain reaction (RQ-PCR), we designed and v...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10226238/ https://www.ncbi.nlm.nih.gov/pubmed/37248544 http://dx.doi.org/10.1186/s12935-023-02938-2 |