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Development and validation of sensitive BCR::ABL1 fusion gene quantitation using next-generation sequencing

BACKGROUND: BCR::ABL1 fusion has significant prognostic value and is screened for chronic myeloid leukemia (CML) disease monitoring as a part of routine molecular testing. To overcome the limitations of the current standard real-time quantitative polymerase chain reaction (RQ-PCR), we designed and v...

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Detalles Bibliográficos
Autores principales: Lee, Hyeonah, Seo, Jieun, Shin, Saeam, Lee, Seung-Tae, Choi, Jong Rak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10226238/
https://www.ncbi.nlm.nih.gov/pubmed/37248544
http://dx.doi.org/10.1186/s12935-023-02938-2