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Experimental hepatic encephalopathy causes early but sustained glial transcriptional changes

Hepatic encephalopathy (HE) is a common complication of liver cirrhosis, associated with high morbidity and mortality, for which no brain-targeted therapies exist at present. The interplay between hyperammonemia and inflammation is thought to drive HE development. As such, astrocytes, the most impor...

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Detalles Bibliográficos
Autores principales: Claeys, Wouter, Van Hoecke, Lien, Lernout, Hannah, De Nolf, Clint, Van Imschoot, Griet, Van Wonterghem, Elien, Verhaege, Daan, Castelein, Jonas, Geerts, Anja, Van Steenkiste, Christophe, Vandenbroucke, Roosmarijn E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10226265/
https://www.ncbi.nlm.nih.gov/pubmed/37248507
http://dx.doi.org/10.1186/s12974-023-02814-w