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Comparison of the Ct-values for genomic and subgenomic SARS-CoV-2 RNA reveals limited predictive value for the presence of replication competent virus

SARS-CoV-2 is the causative agent of the acute respiratory disease COVID-19. In addition to the full length positive-sensed, single-stranded genomic RNA (gRNA), viral subgenomic RNAs (sgRNAs) that are required for expression of the 3′ region of the genome are synthesized in virus-infected cells. How...

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Detalles Bibliográficos
Autores principales: Roesmann, Fabian, Jakobsche, Irene, Pallas, Christiane, Wilhelm, Alexander, Raffel, Johanna, Kohmer, Niko, Toptan, Tuna, Berger, Annemarie, Goetsch, Udo, Ciesek, Sandra, Widera, Marek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10226281/
https://www.ncbi.nlm.nih.gov/pubmed/37327554
http://dx.doi.org/10.1016/j.jcv.2023.105499