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Comparison of the Ct-values for genomic and subgenomic SARS-CoV-2 RNA reveals limited predictive value for the presence of replication competent virus
SARS-CoV-2 is the causative agent of the acute respiratory disease COVID-19. In addition to the full length positive-sensed, single-stranded genomic RNA (gRNA), viral subgenomic RNAs (sgRNAs) that are required for expression of the 3′ region of the genome are synthesized in virus-infected cells. How...
Autores principales: | Roesmann, Fabian, Jakobsche, Irene, Pallas, Christiane, Wilhelm, Alexander, Raffel, Johanna, Kohmer, Niko, Toptan, Tuna, Berger, Annemarie, Goetsch, Udo, Ciesek, Sandra, Widera, Marek |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier B.V.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10226281/ https://www.ncbi.nlm.nih.gov/pubmed/37327554 http://dx.doi.org/10.1016/j.jcv.2023.105499 |
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