The SAGA HAT module is tethered by its SWIRM domain and modulates activity of the SAGA DUB module

The SAGA (Spt-Ada-Gcn5 acetyltransferase) complex is a transcriptional co-activator that both acetylates and deubiquitinates histones. The histone acetyltransferase (HAT) subunit, Gcn5, is part of a subcomplex of SAGA called the HAT module. A minimal HAT module complex containing Gcn5 bound to Ada2...

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Detalles Bibliográficos
Autores principales: Haile, Sara T., Rahman, Sanim, Fields, James K., Orsburn, Benjamin C., Bumpus, Namandjé N., Wolberger, Cynthia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10226619/
https://www.ncbi.nlm.nih.gov/pubmed/36965704
http://dx.doi.org/10.1016/j.bbagrm.2023.194929

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10226619/
https://www.ncbi.nlm.nih.gov/pubmed/36965704
http://dx.doi.org/10.1016/j.bbagrm.2023.194929

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