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The SAGA HAT module is tethered by its SWIRM domain and modulates activity of the SAGA DUB module
The SAGA (Spt-Ada-Gcn5 acetyltransferase) complex is a transcriptional co-activator that both acetylates and deubiquitinates histones. The histone acetyltransferase (HAT) subunit, Gcn5, is part of a subcomplex of SAGA called the HAT module. A minimal HAT module complex containing Gcn5 bound to Ada2...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10226619/ https://www.ncbi.nlm.nih.gov/pubmed/36965704 http://dx.doi.org/10.1016/j.bbagrm.2023.194929 |