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The relevance of acid sphingomyelinase as a potential target for therapeutic intervention in hepatic disorders: current scenario and anticipated trends

Acid sphingomyelinase (ASMase) serves as one of the most remarkable enzymes in sphingolipid biology. ASMase facilitates the hydrolysis of sphingomyelin, yielding ceramide and phosphorylcholine via the phospholipase C signal transduction pathway. Owing to its prominent intervention in apoptosis, ASMa...

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Detalles Bibliográficos
Autores principales: Mir, Ishfaq Hassan, Thirunavukkarasu, Chinnasamy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10226719/
https://www.ncbi.nlm.nih.gov/pubmed/37248308
http://dx.doi.org/10.1007/s00204-023-03529-w