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miR-186 induces tetraploidy in arsenic exposed human keratinocytes

Chronic inorganic arsenic (iAs) exposure in drinking water is a global issue affecting >225 million people. Skin is a major target organ for iAs. miRNA dysregulation and chromosomal instability (CIN) are proposed mechanisms of iAs-induced carcinogenesis. CIN is a cancer hallmark and tetraploid ce...

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Detalles Bibliográficos
Autores principales: Ferragut Cardoso, Ana P., Nail, Alexandra N., Banerjee, Mayukh, Wise, Sandra S., States, J. Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10226781/
https://www.ncbi.nlm.nih.gov/pubmed/36989553
http://dx.doi.org/10.1016/j.ecoenv.2023.114823