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The nuclear lamina couples mechanical forces to cell fate in the preimplantation embryo via actin organization

During preimplantation development, contractile forces generated at the apical cortex segregate cells into inner and outer positions of the embryo, establishing the inner cell mass (ICM) and trophectoderm. To which extent these forces influence ICM-trophectoderm fate remains unresolved. Here, we fou...

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Detalles Bibliográficos
Autores principales: Skory, Robin M., Moverley, Adam A., Ardestani, Goli, Alvarez, Yanina, Domingo-Muelas, Ana, Pomp, Oz, Hernandez, Blake, Tetlak, Piotr, Bissiere, Stephanie, Stern, Claudio D., Sakkas, Denny, Plachta, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10226985/
https://www.ncbi.nlm.nih.gov/pubmed/37248263
http://dx.doi.org/10.1038/s41467-023-38770-5